NFkB-p100(Ab-870) Antibody

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NFkB-p100 Antibody
NFkB-p100 Antibody

NFkB-p100(Ab-870) Antibody

Catalog No : 21016


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SKU: 21016. Category: .

Product Name

NFkB-p100(Ab-870) Antibody

Host Species

Rabbit

Clonality

 Polyclonal

Purification

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Applications

WB IHC

Reactivity

Hu Ms Rt     

Specificity

The antibody detects endogenous level of total NFkB-p100 protein.

Immunogen

Peptide-KLH. Peptide sequence around aa.868~872 (Y-G-S-Q-S) derived from Human NFkB-p100.

Target Name

NFkB-p100

Alternative Name

DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10; Lyt10; NFKB2

SDS-PAGE MW

120kd

Accession No

Q00653; NP_001070961.1

Concentration

1.0mg/ml

Formulation

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for a short term use.

 

Application:

Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100

Background

NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.

Qu Z, et al. (2004) J Biol Chem; 279(43): 44563-72.
Xiao G, et al. (2001) J Biol Chem 7(2): 401-9.

Sizes

100ul, 50ul

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