NFκB-p105(Phospho-Ser893) Antibody

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Histone H3(Acetyl-Lys23) Rabbit Polyclonal Antibody
NFκB-p105(Phospho-Ser893) Antibody

NFκB-p105(Phospho-Ser893) Antibody

Catalog No : 11018


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SKU: 11018. Category: .

Product Name

NFκB-p105(Phospho-Ser893) Antibody

Host Species

Rabbit

Clonality

 Polyclonal

Purification

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Applications

 IHC IF

Reactivity

Hu Ms Rt

Specificity

The antibody detects endogenous level of total NFkB-p105 protein.

Immunogen

Peptide-KLH. Peptide sequence around aa.891~895 (A-S-S-P-V) derived from Human NFκB-p105.

Target Name

NFκB-p105

Alternative Name

KBF1; NF-kB1; NFkappaB

Modification

Phospho-Ser893

SDS-PAGE MW

120kd

Accession No

P19838; NP_001158884.1

Concentration

1.0mg/ml

Formulation

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage

Store at -20°C.

Application

Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:200

Background

Background

NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.

Sizes

100ul, 50ul

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